NewHa+® crosslinked HA is available in a cosmetic-grade powder and an injection-grade gel. Each form has its own specification, quality profile and intended development route.
NewHa+® Crosslinked Sodium Hyaluronate is a crosslinked HA product family. Buyers may also encounter the names Crosslinked Hyaluronic Acid, Crosslinked HA and Sodium Hyaluronate Crosspolymer. The gel form may be described as a crosslinked hyaluronic acid hydrogel.
The powder is a dry raw material for topical cosmetic formulation work. The gel is a prepared viscous system for evaluation by qualified organizations developing regulated injectable products. They are not same: each form has its own specification, COA and technical approval route.
| Item | Details |
| Product family | NewHa+® Crosslinked Sodium Hyaluronate |
| Page reference | CAS 105524-32-1 |
| Available forms | Cosmetic-grade powder; injection-grade gel |
| Powder appearance | White or off-white powder or fibrous particles |
| Gel appearance | Transparent or semi-transparent viscous colloid without visible foreign matter |
| Powder content | 95.0%–105.0% on the dried substance |
| Powder molecular weight | Reported result: >3.0 × 10⁶ Da |
| Gel pH | 6.5–7.5 |
| Gel dynamic viscosity | 45,000–120,000 mPa·s |
| Documents | Separate reference COAs for powder and gel; request current documents for the selected grade |
| MOQ and lead time | Confirmed with the current quotation |
| Grade and form | Key characteristics | Typical selection context | Main technical focus |
| Cosmetic-grade powder | White or off-white powder or fibrous particles; content and molecular-weight reporting on the powder specification | Topical cosmetic formulation development, including water-rich and emulsion systems | Dispersion, hydration, clarity, pH, viscosity, preservative compatibility and finished-formula stability |
| Injection-grade gel | Transparent or semi-transparent viscous colloid; defined particle-size, rheology, extrusion, sterility and endotoxin criteria | Regulated injectable-gel research, product development and quality evaluation by qualified organizations | Rheology, particle-size distribution, extrusion behavior, degradation, sterility, endotoxin and packaging compatibility |
The powder and gel are not alternative packaging formats for the same grade. Choose by application and form first, then compare the relevant content, molecular-weight, rheology, particle-size and microbiological criteria.
The powder grade is a dry Crosslinked Sodium Hyaluronate raw material for cosmetic formulation work. Its reference COA covers identity, solution appearance, pH, content, molecular-weight reporting and microbiological quality.
The table separates the acceptance criteria shown on the reference COA from its reported batch result.
| Test item | Reference acceptance criterion | Reference batch result |
|---|---|---|
| Appearance | White or off-white powder or fibrous particles | Complies |
| Glucuronic acid reaction | Purple-red reaction under the stated identification procedure | Complies |
| Appearance of solution | Clear; A600 nm ≤0.01 | Clear; A600 nm = 0.001 |
| pH | 5.5–8.0 in a 0.5% solution | 7.6 |
| Light transmittance | Clear; T550 nm ≥99.0% | 99.6% |
| Burning residue | ≤18.0% | 17.1% |
| Loss on drying | ≤15.0% | 11.7% |
| Protein content | ≤0.1% | <0.05% |
| Bacterial endotoxins | <0.5 IU/mg | <0.5 IU/mg |
Serums and Essences
The powder grade can be assessed in water-rich serums and essences that use Sodium Hyaluronate Crosspolymer as a humectant and skin-conditioning ingredient. Establish a suitable dispersion process, then assess clarity, pH, viscosity and preservative compatibility before scale-up.
Gels and Mask Essences
Crosslinked HA powder can be considered for gels and mask essences where formula texture is part of the development target. Assess uniform dispersion, final viscosity, microbial control and package stability.
Creams and Lotions
In emulsions, the powder grade may be introduced through an aqueous-phase process established for the finished formula. Assess compatibility with emulsifiers, electrolytes, preservatives and other polymers, then verify viscosity and stability before scale-up.
The gel grade is a transparent or semi-transparent viscous colloid with defined osmotic pressure, particle-size, rheology, extrusion, residue, sterility and endotoxin criteria.
It is intended for evaluation by qualified organizations developing regulated injectable products. The grade and its COA do not by themselves establish finished-device approval or market authorization.
| Test item | Reference acceptance criterion | Reference batch result |
| Appearance | Transparent or semi-transparent viscous colloid without visible foreign matter | Complies |
| Effective usage amount | 90%–120% of the labeled amount | 111% |
| Identification | Meets the stated requirements | Complies |
| UV absorption at 260 nm | ≤1.0 | 0.24 |
| UV absorption at 280 nm | ≤1.0 | 0.19 |
| pH | 6.5–7.5 | 7.2 |
| Osmotic pressure | 270–350 mOsmol/kg | 334 mOsmol/kg |
| Heavy metal content | ≤5 μg/g | Complies |
A reference COA shows the available test profile and one batch result. Commercial qualification should use the current specification and the lot-specific COA for the applicable powder or gel batch.
| Document | Availability |
|---|---|
| Powder reference COA | Available for the cosmetic-grade powder |
| Gel reference COA | Available for the injection-grade gel |
| Current product specification or TDS | Request for the selected form and grade |
| Lot-specific COA | Request for the applicable commercial batch |
| Additional quality or destination-market documents | Include the country and required document scope in the enquiry |
1.Improve skin barrier
2.Reduce water loss in the stratum corneum
3.Resist UV intrusion
4.Maintain multiple times of moisture
5.Form a strong surface protective film
6. Hyaluronic acid is naturally present in the human body, making it extremely safe. It can be completely absorbed and metabolized by the body. The cross-linked sodium hyaluronic acid gel has good biocompatibility and possesses the ability to resist hyaluronidase degradation, thus allowing hyaluronic acid to remain in the body for a long time and stabilize the exertion of its unique physical and chemical properties.
7. The cross-linked sodium hyaluronic acid gel has good supporting force, viscosity, and elasticity, and is not prone to diffusion or displacement. Therefore, it has a good filling and shaping effect and the shaping lasts for a long time.
8. The rate of metabolism is uniform. The speed of absorption is related to the fullness and firmness of each person’s skin.
100g/bottle,500g/bottle,1kg/bottle.
Standard pack size, alternative packaging, sample quantity, MOQ and lead time are confirmed with the current quotation.
These terms may differ between the powder and gel because the two forms have different handling, packaging and project requirements.
No. The cosmetic-grade powder is intended for topical formulation work, while the injection-grade gel follows a separate specification and development route. Each form has its own COA.
No. It is a raw-material gel for regulated product development.
Yes. Renew can compare the requested limit and test method with the available powder or gel specification. Include the intended application in your enquiry.
Yes. Request the cosmetic-grade powder, injection-grade gel or both. Sample quantity and availability are confirmed by grade; include the intended application and destination country.
MOQ, sample quantity and lead time are confirmed with the current quotation.
Provide the required form, target specification, estimated quantity, application, destination country, packaging request and document list. Renew will confirm the applicable grade, sample status and commercial terms.
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