交联透明质酸钠 CAS 105524-32-1

NewHa+® crosslinked HA is available in a cosmetic-grade powder and an injection-grade gel. Each form has its own specification, quality profile and intended development route.

  • CAS: 105524-32-1
    纯度:95%以上
    保存期:2年
  • Cosmetic powder and injection-grade gel options
  • Separate technical specifications for each form
  • Grade-specific reference COAs available
  • Samples, documents and commercial terms confirmed by grade

 

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产品概述

NewHa+® Crosslinked Sodium Hyaluronate is a crosslinked HA product family. Buyers may also encounter the names Crosslinked Hyaluronic Acid, Crosslinked HA and Sodium Hyaluronate Crosspolymer. The gel form may be described as a crosslinked hyaluronic acid hydrogel.

The powder is a dry raw material for topical cosmetic formulation work. The gel is a prepared viscous system for evaluation by qualified organizations developing regulated injectable products. They are not same: each form has its own specification, COA and technical approval route.

快速采购信息

项目 详情
Product family NewHa+® Crosslinked Sodium Hyaluronate
Page reference CAS 105524-32-1
Available forms Cosmetic-grade powder; injection-grade gel
Powder appearance White or off-white powder or fibrous particles
Gel appearance Transparent or semi-transparent viscous colloid without visible foreign matter
Powder content 95.0%–105.0% on the dried substance
Powder molecular weight Reported result: >3.0 × 10⁶ Da
Gel pH 6.5–7.5
Gel dynamic viscosity 45,000–120,000 mPa·s
Documents Separate reference COAs for powder and gel; request current documents for the selected grade
MOQ and lead time 已根据当前报价确认

Powder or Gel: Choose the Correct Crosslinked HA Grade

Grade and form Key characteristics Typical selection context Main technical focus
Cosmetic-grade powder White or off-white powder or fibrous particles; content and molecular-weight reporting on the powder specification Topical cosmetic formulation development, including water-rich and emulsion systems Dispersion, hydration, clarity, pH, viscosity, preservative compatibility and finished-formula stability
Injection-grade gel Transparent or semi-transparent viscous colloid; defined particle-size, rheology, extrusion, sterility and endotoxin criteria Regulated injectable-gel research, product development and quality evaluation by qualified organizations Rheology, particle-size distribution, extrusion behavior, degradation, sterility, endotoxin and packaging compatibility

The powder and gel are not alternative packaging formats for the same grade. Choose by application and form first, then compare the relevant content, molecular-weight, rheology, particle-size and microbiological criteria.

Cosmetic-Grade Crosslinked Sodium Hyaluronate Powder

The powder grade is a dry Crosslinked Sodium Hyaluronate raw material for cosmetic formulation work. Its reference COA covers identity, solution appearance, pH, content, molecular-weight reporting and microbiological quality.

Powder Grade Technical Specification

The table separates the acceptance criteria shown on the reference COA from its reported batch result.

Test item Reference acceptance criterion Reference batch result
外观 White or off-white powder or fibrous particles 符合
Glucuronic acid reaction Purple-red reaction under the stated identification procedure 符合
溶液外观 透明;A600 nm ≤0.01 Clear; A600 nm = 0.001
pH 5.5–8.0 in a 0.5% solution 7.6
Light transmittance Clear; T550 nm ≥99.0% 99.6%
Burning residue ≤18.0% 17.1%
干燥损失 ≤15.0% 11.7%
蛋白质含量 ≤0.1% <0.05%
Bacterial endotoxins <0.5 IU/mg <0.5 IU/mg

Cosmetic Formulation Applications

精华液和精华

The powder grade can be assessed in water-rich serums and essences that use Sodium Hyaluronate Crosspolymer as a humectant and skin-conditioning ingredient. Establish a suitable dispersion process, then assess clarity, pH, viscosity and preservative compatibility before scale-up.

Gels and Mask Essences

Crosslinked HA powder can be considered for gels and mask essences where formula texture is part of the development target. Assess uniform dispersion, final viscosity, microbial control and package stability.

面霜和乳液

In emulsions, the powder grade may be introduced through an aqueous-phase process established for the finished formula. Assess compatibility with emulsifiers, electrolytes, preservatives and other polymers, then verify viscosity and stability before scale-up.

Injection-Grade Crosslinked Sodium Hyaluronate Gel

The gel grade is a transparent or semi-transparent viscous colloid with defined osmotic pressure, particle-size, rheology, extrusion, residue, sterility and endotoxin criteria.

It is intended for evaluation by qualified organizations developing regulated injectable products. The grade and its COA do not by themselves establish finished-device approval or market authorization.

Gel Grade Technical Specification

Test item Reference acceptance criterion Reference batch result
外观 Transparent or semi-transparent viscous colloid without visible foreign matter 符合
Effective usage amount 90%–120% of the labeled amount 111%
鉴别 Meets the stated requirements 符合
UV absorption at 260 nm ≤1.0 0.24
UV absorption at 280 nm ≤1.0 0.19
pH 6.5–7.5 7.2
Osmotic pressure 270–350 mOsmol/kg 334 mOsmol/kg
Heavy metal content ≤5 μg/g 符合

质量和批次文件

A reference COA shows the available test profile and one batch result. Commercial qualification should use the current specification and the lot-specific COA for the applicable powder or gel batch.

文档 可用性
Powder reference COA Available for the cosmetic-grade powder
Gel reference COA Available for the injection-grade gel
Current product specification or TDS Request for the selected form and grade
每批次专属的合格证书 Request for the applicable commercial batch
Additional quality or destination-market documents Include the country and required document scope in the enquiry

特征

1.改善皮肤屏障

2.减少角质层的水分流失

3.抗紫外线侵入

4.保持数倍的水分

5.形成牢固的表面保护膜

6.透明质酸是人体内天然存在的物质,因此非常安全。它可以被人体完全吸收和代谢。交联透明质酸钠凝胶具有良好的生物相容性,具有抗透明质酸酶降解的能力,从而使透明质酸能够在体内长期存在,稳定地发挥其独特的物理和化学特性。.

7.交联透明质酸钠凝胶具有良好的支撑力、粘度和弹性,不易扩散和移位。因此,它具有良好的填充和塑形效果,而且塑形持续时间长。.

8.新陈代谢的速度是均匀的。吸收速度与每个人皮肤的饱满度和紧致度有关。.

Packaging, Storage and Commercial Terms

100克/瓶、500克/瓶、1公斤/瓶。

Standard pack size, alternative packaging, sample quantity, MOQ and lead time are confirmed with the current quotation.

These terms may differ between the powder and gel because the two forms have different handling, packaging and project requirements.

常见问题解答

No. The cosmetic-grade powder is intended for topical formulation work, while the injection-grade gel follows a separate specification and development route. Each form has its own COA.

No. It is a raw-material gel for regulated product development. 

Yes. Renew can compare the requested limit and test method with the available powder or gel specification. Include the intended application in your enquiry.

Yes. Request the cosmetic-grade powder, injection-grade gel or both. Sample quantity and availability are confirmed by grade; include the intended application and destination country.

MOQ, sample quantity and lead time are confirmed with the current quotation.

Provide the required form, target specification, estimated quantity, application, destination country, packaging request and document list. Renew will confirm the applicable grade, sample status and commercial terms.

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