架橋ヒアルロン酸ナトリウム CAS 105524-32-1

NewHa+® crosslinked HA is available in a cosmetic-grade powder and an injection-grade gel. Each form has its own specification, quality profile and intended development route.

  • CAS: 105524-32-1
    純度:95%min
    保存期間:2年
  • Cosmetic powder and injection-grade gel options
  • Separate technical specifications for each form
  • Grade-specific reference COAs available
  • Samples, documents and commercial terms confirmed by grade

 

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製品概要

NewHa+® Crosslinked Sodium Hyaluronate is a crosslinked HA product family. Buyers may also encounter the names Crosslinked Hyaluronic Acid, Crosslinked HA and Sodium Hyaluronate Crosspolymer. The gel form may be described as a crosslinked hyaluronic acid hydrogel.

The powder is a dry raw material for topical cosmetic formulation work. The gel is a prepared viscous system for evaluation by qualified organizations developing regulated injectable products. They are not same: each form has its own specification, COA and technical approval route.

調達に関する概要情報

品目 Details
Product family NewHa+® Crosslinked Sodium Hyaluronate
Page reference CAS 105524-32-1
Available forms Cosmetic-grade powder; injection-grade gel
Powder appearance White or off-white powder or fibrous particles
Gel appearance Transparent or semi-transparent viscous colloid without visible foreign matter
Powder content 95.0%–105.0% on the dried substance
Powder molecular weight Reported result: >3.0 × 10⁶ Da
Gel pH 6.5–7.5
Gel dynamic viscosity 45,000–120,000 mPa·s
Documents Separate reference COAs for powder and gel; request current documents for the selected grade
MOQ and lead time Confirmed with the current quotation

Powder or Gel: Choose the Correct Crosslinked HA Grade

Grade and form Key characteristics Typical selection context Main technical focus
Cosmetic-grade powder White or off-white powder or fibrous particles; content and molecular-weight reporting on the powder specification Topical cosmetic formulation development, including water-rich and emulsion systems Dispersion, hydration, clarity, pH, viscosity, preservative compatibility and finished-formula stability
Injection-grade gel Transparent or semi-transparent viscous colloid; defined particle-size, rheology, extrusion, sterility and endotoxin criteria Regulated injectable-gel research, product development and quality evaluation by qualified organizations Rheology, particle-size distribution, extrusion behavior, degradation, sterility, endotoxin and packaging compatibility

The powder and gel are not alternative packaging formats for the same grade. Choose by application and form first, then compare the relevant content, molecular-weight, rheology, particle-size and microbiological criteria.

Cosmetic-Grade Crosslinked Sodium Hyaluronate Powder

The powder grade is a dry Crosslinked Sodium Hyaluronate raw material for cosmetic formulation work. Its reference COA covers identity, solution appearance, pH, content, molecular-weight reporting and microbiological quality.

Powder Grade Technical Specification

The table separates the acceptance criteria shown on the reference COA from its reported batch result.

Test item Reference acceptance criterion Reference batch result
外観 White or off-white powder or fibrous particles 準拠しています
Glucuronic acid reaction Purple-red reaction under the stated identification procedure 準拠しています
溶液の外観 Clear; A600 nm ≤0.01 Clear; A600 nm = 0.001
pH 5.5–8.0 in a 0.5% solution 7.6
Light transmittance Clear; T550 nm ≥99.0% 99.6%
Burning residue ≤18.0% 17.1%
乾燥減量 ≤15.0% 11.7%
タンパク質含有量 ≤0.1% <0.05%
Bacterial endotoxins <0.5 IU/mg <0.5 IU/mg

Cosmetic Formulation Applications

美容液・エッセンス

The powder grade can be assessed in water-rich serums and essences that use Sodium Hyaluronate Crosspolymer as a humectant and skin-conditioning ingredient. Establish a suitable dispersion process, then assess clarity, pH, viscosity and preservative compatibility before scale-up.

Gels and Mask Essences

Crosslinked HA powder can be considered for gels and mask essences where formula texture is part of the development target. Assess uniform dispersion, final viscosity, microbial control and package stability.

クリームとローション

In emulsions, the powder grade may be introduced through an aqueous-phase process established for the finished formula. Assess compatibility with emulsifiers, electrolytes, preservatives and other polymers, then verify viscosity and stability before scale-up.

Injection-Grade Crosslinked Sodium Hyaluronate Gel

The gel grade is a transparent or semi-transparent viscous colloid with defined osmotic pressure, particle-size, rheology, extrusion, residue, sterility and endotoxin criteria.

It is intended for evaluation by qualified organizations developing regulated injectable products. The grade and its COA do not by themselves establish finished-device approval or market authorization.

Gel Grade Technical Specification

Test item Reference acceptance criterion Reference batch result
外観 Transparent or semi-transparent viscous colloid without visible foreign matter 準拠しています
Effective usage amount 90%–120% of the labeled amount 111%
識別 Meets the stated requirements 準拠しています
UV absorption at 260 nm ≤1.0 0.24
UV absorption at 280 nm ≤1.0 0.19
pH 6.5–7.5 7.2
Osmotic pressure 270–350 mOsmol/kg 334 mOsmol/kg
Heavy metal content ≤5 μg/g 準拠しています

品質およびロットに関する文書

A reference COA shows the available test profile and one batch result. Commercial qualification should use the current specification and the lot-specific COA for the applicable powder or gel batch.

文書 在庫状況
Powder reference COA Available for the cosmetic-grade powder
Gel reference COA Available for the injection-grade gel
Current product specification or TDS Request for the selected form and grade
ロットごとのCOA Request for the applicable commercial batch
Additional quality or destination-market documents Include the country and required document scope in the enquiry

特徴

1.Improve 皮の障壁

2.角質層の水分損失を減らす

3.Resist 紫外線侵入

4.複数回の水分保持

5.Form 強い表面の保護フィルム

6.ヒアルロン酸は人体に自然に存在するもので、非常に安全です。体内で完全に吸収・代謝される。架橋されたヒアルロン酸ナトリウムゲルは生体適合性に優れ、ヒアルロニダーゼ分解に抵抗する能力を持っているため、ヒアルロン酸は長期間体内に留まり、そのユニークな物理的・化学的特性の発揮を安定させることができる。.

7.架橋ヒアルロン酸ナトリウムゲルは、支持力、粘性、弾力性に優れ、拡散や変位が起こりにくい。そのため、充填・形成効果が高く、形成が長時間持続します。.

8.新陳代謝の速度は均一です。吸収の速さは、人それぞれの肌のふっくら感やハリ感に関係する。.

Packaging, Storage and Commercial Terms

100g/ボトル、500g/ボトル、1kg/ボトル。.

Standard pack size, alternative packaging, sample quantity, MOQ and lead time are confirmed with the current quotation.

These terms may differ between the powder and gel because the two forms have different handling, packaging and project requirements.

よくある質問

No. The cosmetic-grade powder is intended for topical formulation work, while the injection-grade gel follows a separate specification and development route. Each form has its own COA.

No. It is a raw-material gel for regulated product development. 

Yes. Renew can compare the requested limit and test method with the available powder or gel specification. Include the intended application in your enquiry.

Yes. Request the cosmetic-grade powder, injection-grade gel or both. Sample quantity and availability are confirmed by grade; include the intended application and destination country.

MOQ, sample quantity and lead time are confirmed with the current quotation.

Provide the required form, target specification, estimated quantity, application, destination country, packaging request and document list. Renew will confirm the applicable grade, sample status and commercial terms.

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