NewHa+® crosslinked HA is available in a cosmetic-grade powder and an injection-grade gel. Each form has its own specification, quality profile and intended development route.
NewHa+® Crosslinked Sodium Hyaluronate is a crosslinked HA product family. Buyers may also encounter the names Crosslinked Hyaluronic Acid, Crosslinked HA and Sodium Hyaluronate Crosspolymer. The gel form may be described as a crosslinked hyaluronic acid hydrogel.
The powder is a dry raw material for topical cosmetic formulation work. The gel is a prepared viscous system for evaluation by qualified organizations developing regulated injectable products. They are not same: each form has its own specification, COA and technical approval route.
| Artículo | Detalles |
| Product family | NewHa+® Crosslinked Sodium Hyaluronate |
| Page reference | CAS 105524-32-1 |
| Available forms | Cosmetic-grade powder; injection-grade gel |
| Powder appearance | White or off-white powder or fibrous particles |
| Gel appearance | Transparent or semi-transparent viscous colloid without visible foreign matter |
| Powder content | 95.0%–105.0% on the dried substance |
| Powder molecular weight | Reported result: >3.0 × 10⁶ Da |
| Gel pH | 6.5–7.5 |
| Gel dynamic viscosity | 45,000–120,000 mPa·s |
| Documentos | Separate reference COAs for powder and gel; request current documents for the selected grade |
| Cantidad mínima de pedido y plazo de entrega | Confirmado según la cotización actual |
| Grade and form | Key characteristics | Typical selection context | Main technical focus |
| Cosmetic-grade powder | White or off-white powder or fibrous particles; content and molecular-weight reporting on the powder specification | Topical cosmetic formulation development, including water-rich and emulsion systems | Dispersion, hydration, clarity, pH, viscosity, preservative compatibility and finished-formula stability |
| Injection-grade gel | Transparent or semi-transparent viscous colloid; defined particle-size, rheology, extrusion, sterility and endotoxin criteria | Regulated injectable-gel research, product development and quality evaluation by qualified organizations | Rheology, particle-size distribution, extrusion behavior, degradation, sterility, endotoxin and packaging compatibility |
The powder and gel are not alternative packaging formats for the same grade. Choose by application and form first, then compare the relevant content, molecular-weight, rheology, particle-size and microbiological criteria.
The powder grade is a dry Crosslinked Sodium Hyaluronate raw material for cosmetic formulation work. Its reference COA covers identity, solution appearance, pH, content, molecular-weight reporting and microbiological quality.
The table separates the acceptance criteria shown on the reference COA from its reported batch result.
| Test item | Reference acceptance criterion | Reference batch result |
|---|---|---|
| Apariencia | White or off-white powder or fibrous particles | Cumple con |
| Glucuronic acid reaction | Purple-red reaction under the stated identification procedure | Cumple con |
| Aspecto de la solución | Clear; A600 nm ≤0.01 | Clear; A600 nm = 0.001 |
| pH | 5.5–8.0 in a 0.5% solution | 7.6 |
| Light transmittance | Clear; T550 nm ≥99.0% | 99.6% |
| Burning residue | ≤18.0% | 17.1% |
| Pérdida por secado | ≤15.0% | 11.7% |
| Contenido en proteínas | ≤0.1% | <0.05% |
| Bacterial endotoxins | <0.5 IU/mg | <0.5 IU/mg |
Sérums y esencias
The powder grade can be assessed in water-rich serums and essences that use Sodium Hyaluronate Crosspolymer as a humectant and skin-conditioning ingredient. Establish a suitable dispersion process, then assess clarity, pH, viscosity and preservative compatibility before scale-up.
Gels and Mask Essences
Crosslinked HA powder can be considered for gels and mask essences where formula texture is part of the development target. Assess uniform dispersion, final viscosity, microbial control and package stability.
Cremas y lociones
In emulsions, the powder grade may be introduced through an aqueous-phase process established for the finished formula. Assess compatibility with emulsifiers, electrolytes, preservatives and other polymers, then verify viscosity and stability before scale-up.
The gel grade is a transparent or semi-transparent viscous colloid with defined osmotic pressure, particle-size, rheology, extrusion, residue, sterility and endotoxin criteria.
It is intended for evaluation by qualified organizations developing regulated injectable products. The grade and its COA do not by themselves establish finished-device approval or market authorization.
| Test item | Reference acceptance criterion | Reference batch result |
| Apariencia | Transparent or semi-transparent viscous colloid without visible foreign matter | Cumple con |
| Effective usage amount | 90%–120% of the labeled amount | 111% |
| Identificación | Meets the stated requirements | Cumple con |
| UV absorption at 260 nm | ≤1.0 | 0.24 |
| UV absorption at 280 nm | ≤1.0 | 0.19 |
| pH | 6.5–7.5 | 7.2 |
| Osmotic pressure | 270–350 mOsmol/kg | 334 mOsmol/kg |
| Heavy metal content | ≤5 μg/g | Cumple con |
A reference COA shows the available test profile and one batch result. Commercial qualification should use the current specification and the lot-specific COA for the applicable powder or gel batch.
| Documento | Disponibilidad |
|---|---|
| Powder reference COA | Available for the cosmetic-grade powder |
| Gel reference COA | Available for the injection-grade gel |
| Current product specification or TDS | Request for the selected form and grade |
| Certificado de autenticidad específico del lote | Request for the applicable commercial batch |
| Additional quality or destination-market documents | Include the country and required document scope in the enquiry |
1.Mejorar la barrera cutánea
2.Reducir la pérdida de agua en el estrato córneo
3.Resiste la intrusión de los rayos UV
4.Mantener varias veces la humedad
5.Forma una fuerte película protectora de la superficie
6. El ácido hialurónico está presente de forma natural en el cuerpo humano, por lo que es extremadamente seguro. Puede ser completamente absorbido y metabolizado por el organismo. El gel de ácido hialurónico sódico reticulado tiene una buena biocompatibilidad y posee la capacidad de resistir la degradación de la hialuronidasa, lo que permite que el ácido hialurónico permanezca en el cuerpo durante mucho tiempo y estabilice el ejercicio de sus propiedades físicas y químicas únicas.
7. El gel de ácido hialurónico sódico reticulado tiene buena fuerza de soporte, viscosidad y elasticidad, y no es propenso a la difusión ni al desplazamiento. Por lo tanto, tiene un buen efecto de relleno y moldeado y el moldeado dura mucho tiempo.
8. El ritmo del metabolismo es uniforme. La velocidad de absorción está relacionada con la plenitud y firmeza de la piel de cada persona.
100g/botella,500g/botella,1kg/botella.
Standard pack size, alternative packaging, sample quantity, MOQ and lead time are confirmed with the current quotation.
These terms may differ between the powder and gel because the two forms have different handling, packaging and project requirements.
No. The cosmetic-grade powder is intended for topical formulation work, while the injection-grade gel follows a separate specification and development route. Each form has its own COA.
No. It is a raw-material gel for regulated product development.
Yes. Renew can compare the requested limit and test method with the available powder or gel specification. Include the intended application in your enquiry.
Yes. Request the cosmetic-grade powder, injection-grade gel or both. Sample quantity and availability are confirmed by grade; include the intended application and destination country.
MOQ, sample quantity and lead time are confirmed with the current quotation.
Provide the required form, target specification, estimated quantity, application, destination country, packaging request and document list. Renew will confirm the applicable grade, sample status and commercial terms.
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