PDRN PN Sodium DNA CAS 9007-49-2

Item Information
Product Name Sodium DNA / Polydeoxyribonucleotide(PDRN)
Grade Cosmetic Grade
Test HPLC/UV
Appearance White or off-white powder
Min Order 1Kg
OEM OEM Packaging Available
Storage 2–8°C, sealed and protected from light
Shelf Life 2 years under the stated storage conditions
Sample 1g sample available

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SALMON DNA Supplier - RENEW

Product Overview

RENEW supplies cosmetic-grade Sodium DNA (polydeoxyribonucleotide/PDRN) powder for topical cosmetic formulation and ingredient evaluation. This raw material can be assessed for serums, ampoules, essences, gels, sheet masks, creams and lotions where formulators need a DNA-derived cosmetic ingredient supported by clear specifications and batch documentation. Because commercial PDRN grades can differ in source, assay, molecular-weight distribution, solubility and microbial limits, buyers should compare the actual specification rather than relying on the product name alone. RENEW can provide COA, TDS, SDS, source information, sample support and specification review to help customers evaluate a suitable grade. Final use level, processing method, stability and regulatory suitability should be confirmed in the finished formulation. No therapeutic or drug claims are intended.

Sodium DNA (PDRN) powder bulk supply for cosmetic manufacturers
Cosmetic-grade Sodium DNA (PDRN) powder

Product Specifications

ITEM STANDARD RESULT
Characters White or off-white powder or fibre polymer or particle White powder
Identification UV:Ratio of absorbance at 260nm and 280nm1.5~2.0 1.8
Odor  Characteristic odor  Complies
Solubility      Slightly soluble in water,insoluble in ethanol  Complies
PH value  5.0~9.0 6.1
Average Molecular Weight ≤1000kD  80kD
Loss on Drying NMT 20.0% 4.8%
Hg NMT1ppm Complies

What is PDRN Raw Material?

PDRN, short for polydeoxyribonucleotide, is a DNA-derived raw material composed of deoxyribonucleotide chains or fragments. Its source, molecular-weight distribution, assay and physical properties may vary between grades. These factors should be reviewed when selecting PDRN for cosmetic formulation.

Salmon-derived PDRN is produced from DNA obtained from salmon reproductive cells and processed into purified DNA fragments. Depending on the grade, the material may vary in assay, molecular-weight distribution, solubility and formulation compatibility. For purchasing and formulation evaluation, confirm the biological source, product specification, TDS and batch-specific COA of the selected grade.

PDRN and PN are related nucleotide-based materials, but the names should not automatically be treated as interchangeable.

PDRN generally refers to shorter DNA fragments with a lower molecular-weight distribution, while PN usually refers to longer-chain polynucleotide material with a higher molecular weight and a more complex structure. However, the exact definition and technical parameters may vary between suppliers and grades.

Buyers should compare molecular-weight information, assay, solubility, source and intended application before selecting a product.

PDRN PN
A Defined DNA Mixture A High-Molecular-Weight Polymer
Polydeoxyribonucleotide PDRN is a DNA-based polymer derived from natural DNA. Itconsists of defined DNA fragments with nucle-otides linked by phosphodiester bonds, form-ing characteristic double-helix segments. PN (Polynucleotide) is a linear or circular mac-romolecular chain formed by connecting nu-cleotides as basic units through phosphodi-ester bonds, with a molecular weight greaterthan 1000 kDa.
Molecular Weight Lower Molecular Weight Higher (>1000kDa)
Spatial Structure-Relatively Simple Segments Spatial Structure-Compact 3D Network
Primary Application-Skin Boosters (Reparative) Primary Application-Dermal Fillers (Structural)
Solubility (in water, heated)-Up to 4% Solubility (in water, heated)-Up to 2%
Bio-stimulation & Tissue Regeneration Structural Support &Volume Restoration

Why Source PDRN Powder From RENEW?

Clear Product Identification
Source, grade, form and key specification items are available for buyer review.

Batch Documentation
Each shipment is supported with a batch-specific COA so buyers can check the supplied material against the agreed specification.

Sample Evaluation Support
Samples can be arranged for laboratory screening before bulk purchasing.

Practical Supply Communication
Our team can discuss grade selection, packaging, documentation and order requirements based on the customer’s project.

SALMON DNA (PDRN)EXTRACTION PROCESS

Sodium DNA Powder for Cosmetic Applications

Cosmetic-grade Sodium DNA (PDRN) powder can be evaluated for use in water-based and emulsion cosmetic formulations. During formulation development, assess its dissolution, compatibility and stability under the intended processing and storage conditions. Final suitability depends on the supplied grade, use level and complete formulation.

  1. Facial Serums and Ampoules: This ingredient can be evaluated in lightweight serums and ampoules formulated for hydration and skin comfort. Confirm dissolution, clarity, pH compatibility and preservative performance in the finished product.
  2. Essences and Toners: For water-rich essences and toners, evaluate dispersion, solution clarity and microbial stability. Laboratory testing is recommended before confirming the use level and production process.
  3. Gels and Sheet Masks: Sodium DNA powder can also be assessed in cosmetic gels and sheet mask essences. Check uniform dispersion, preservative compatibility and packaging stability before scale-up.
  4. Creams and Lotions: For emulsion systems, introduce the ingredient through a validated aqueous-phase process. Evaluate its compatibility with emulsifiers, electrolytes, preservatives and other formulation ingredients.
Sodium DNA - PDRN Applications

PDRN Supply Support

From Initial Testing to Commercial Orders RENEW supplies cosmetic-grade Sodium DNA (PDRN) powder for skincare formulation and product development. Whether you are testing a new formula or preparing for commercial production, we can provide the product information needed for your evaluation.

Available support includes:

  • Product specification, TDS and SDS
  • Batch-specific COA
  • Sample and packaging information
  • Quotation based on your required quantity
  • Document support for your destination market

Tell us your application, estimated quantity, destination market and required documents. We will prepare the appropriate product information and quotation for your project.

Packaging and Storage

Packaging

  • Cosmetic-grade Sodium DNA (PDRN) powder is supplied in 1 g bottles as the standard packaging format. Other pack sizes can be discussed based on the required quantity and purchasing needs.
  • 100g/bottle. 1kg/bottle.

Storage

  • Keep the product in its original container with the package tightly closed. Store at 2–8°C, protected from light, moisture and heat.
  • The shelf life is two years when the unopened product is stored under the recommended conditions. After opening, minimize exposure to moisture and contamination, and close the container promptly after use.
Sodium DNA (PDRN) powder packing
Sodium DNA (PDRN) powder bulk supply for cosmetic manufacturers

Our Advantages

1.Production processes including plant-based, animal-based and biotechnological methods are carried out simultaneously, meeting the needs of different customers.

2.The assays are different, the viscosities are different, and the states are different. A gentle production process of DNA designed to protect the double strand structure of DNA and ensure a very high level of purity.Assay can reach ≥99%.

3.Plant-based PDRN can customize raw materials according to customer demands, such as ginseng, brown algae, pinus massoniana, rose, and snow grass,enabling personalized requirements.

4.Large range of Molecular Weight.

Features

1.Tissue repair and regeneration: Accelerate fibroblast proliferation, migration and collagen/elastin synthesis to repair damaged tissues.

2.Vascular proliferation: Stimulates the growth of vascular endothelial cells, improves local microcirculation, and provides more oxygen and nutrients to the damaged area.

3.Anti-inflammatory effect: Regulates the expression of inflammatory factors, reduces the inflammatory response in tissues, and creates a more conducive environment for repair.

4.Cell protection: Reduces oxidative stress damage and protects cell vitality.

Quality Control for PDRN Powder

RENEW controls cosmetic-grade Sodium DNA (PDRN) powder from incoming-material review through finished-batch release. Each batch is evaluated against the applicable product specification before supply.

Source and Material Review

Source information, material identity and incoming documentation are reviewed before processing. This helps ensure that the correct material and grade enter the production process.

Finished-Batch Testing

Each finished batch is tested against its product specification. Depending on the grade, evaluated parameters may include appearance, assay, molecular-weight information, solubility, moisture and other specified quality indicators.

In-Process Control

In-Process Control: Key processing and handling conditions are monitored under documented procedures to maintain batch consistency and control the risk of contamination or material mix-up.

COA and Batch Traceability

A batch-specific COA can be provided for the relevant lot, showing its reported quality results. Batch identification allows the supplied product to be matched with the corresponding quality documentation.

About RENEW

RENEW Ingredients Co., Ltd. supplies specialty biomaterial ingredients for cosmetic formulation and product development. Starting with carbohydrate-based raw materials, the company built practical experience in biological processing, quality control and international supply.

In 2019, RENEW expanded into sodium hyaluronate and nucleotide-based ingredients, including cosmetic-grade Sodium DNA (PDRN). Our team works with formulation developers, cosmetic manufacturers and ingredient buyers to support grade selection, product evaluation and commercial sourcing.

FAQ

The minimum order quantity for the standard grade is 1 g, supplied in a 1 g bottle.

RENEW can provide COA, TDS, SDS and other files according to the requested grade and purchasing stage.

Evaluation samples are also available on request. Please provide your intended application, formulation type, destination country and required quantity so that RENEW can confirm the appropriate sample and shipping arrangements.

Compare the product grade, source, specification, assay, molecular-weight information and batch consistency. Buyers should also confirm the availability of a current TDS, SDS, batch-specific COA, evaluation samples, suitable packaging and technical support.

PDRN and Sodium DNA are often used together in commercial product descriptions, but the terminology may vary between grades and suppliers. Buyers should review the product specification, label name, source information and COA to confirm the identity of the supplied material.

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