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Hydrolyzed Hyaluronic Acid CAS 9004-61-9

Cosmetic-grade Hydrolyzed Hyaluronic Acid for serums, toners, masks and emulsion formulations, supported by current technical and batch documents.

CAS: 9004-61-9
Purity: 92%min
Molecular Formula: C14H22NNaO11
Molecular Weight：/
EINECS：232-678-0
PH specification: 2.5–5.0
Standard Packaging: 1 kg/bag
Storage Period: 2 year ;Synonyms:[BETA-SODIUM-GLUCONATE-(1,3)-BETA-N-ACETYL-D-GLUCOSAMINE-1,4-]N; COPOLY(BETA-GLUCURONICACID-[1->3]-BETA-N-ACETYLGLUCOSAMINE-[1->4]SODIUMSALT; HYALURONICACIDNA-SALT; HYALURONICACID,SODIUMSALT,STREPTOCOCCUSSPECIE; HYALURONICACIDSODIUM; HYALURONICACIDHUMANSODIUMSALT; acidhyaluronic;sodiuM(2S,3S,4R,5R,6R)-3-((2S,3R,5S,6R)-3-acetaMido-5-hydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yloxy)-4,5,6-trihydroxytetrahydro-2H-pyran-2-carboxylate

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Product Overview

Renew supplies Hydrolyzed Hyaluronic Acid under CAS 9004-61-9 as a white or almost white cosmetic-grade powder or granules. It is intended for formulation trials, raw-material qualification and commercial sourcing in skin-care and personal-care projects.

The specification covers identity, content, molecular-weight, optical, physicochemical and microbiological test items. Key controls include glucuronic acid content, sodium hyaluronate content, pH, transparency, intrinsic viscosity, protein, heavy metals and microbiological limits.

Molecular weight is an important purchasing variable for hydrolyzed hyaluronic-acid materials. Buyers with a defined target should include the required value or range and preferred test method in the enquiry so the correct grade information can be reviewed.

Cosmetics commonly used sodium hyaluronate, are relatively large molecular weight structure, skin external use, is not conducive to absorption basically stay on the stratum corneum. Therefore, the polymer sodium hyaluronate is degraded by biological enzymes to obtain sodium hyaluronate with a smaller molecular weight, which is called “NewHa® Hydrolyzed Hyaluronic Acid”.

Compared with regular hyaluronic acid, Hydrolyzed Sodium Hyaluronate (CAS 9004-61-9) penetrates the skin more effectively, providing deep hydration and improved elasticity from within.

It is widely used in cosmetic grade sodium hyaluronate formulations, including facial serums, lotions, masks, and essence products that aim to deliver long-lasting moisture and anti-aging benefits.

NewHa® Hydrolyzed Hyaluronic Acid and hydrolyzed sodium hyaluronate are not the same product, and the PH of hydrolyzed hyaluronic acid sold on the market is generally between 2.5 and 5.0. Some people think that the molecular weight must be below 10kDa to become hydrolyzed hyaluronic acid, but some people think that the molecular weight below 50kDa is hydrolyzed hyaluronic acid. As a professional China sodium hyaluronate manufacturer, we ensure consistent molecular weight distribution, high purity, and excellent biocompatibility, meeting international cosmetic ingredient standards.

Choose the Correct Hyaluronate Grade

Renew manages Hydrolyzed Hyaluronic Acid and Oligo Sodium Hyaluronate as separate commercial products. This page covers Hydrolyzed Hyaluronic Acid under CAS 9004-61-9. The separate Oligo Sodium Hyaluronate / Hydrolyzed Sodium Hyaluronate page covers the sodium hyaluronate CAS 9067-32-7, with an average molecular-weight specification of no more than 10,000 Da.

Do not use the two product names as automatic synonyms in purchasing documents or formulation records. State the required product name, CAS reference and target molecular-weight information in the enquiry.

Technical Specification

Test Item	Specification
Appearance	White or almost white powder or granules
Infrared absorption	The infrared absorption spectrum should be consistent with the control spectrum
Sodium salt identification reaction	Should show the positive reaction of sodium salt
Glucuronic acid content (%)	≥45.0
Sodium hyaluronate content (%)	≥92.0
Average molecular weight	Measured value (80% -120% of the labeled quantity)
Absorbance	≤0.25
Transparency (%)	≥99.0
Intrinsic viscosity value (dL/g)	Actual value
Dry weight loss (%)	≤10.0
pH	2.5-5.0
Heavy metal (in lead,mg/kg)	≤20
Protein content (%)	≤0.10
Total Colony Number (CFU/g)	≤100
Fungi and yeasts (CFU/g)	≤50
Staphylococcus Aureus	Negative
Pseudomonas Aeruginosas	Negative

Hydrolyzed Hyaluronic Acid for Cosmetic Applications

Hydrolyzed Hyaluronic Acid can be evaluated in water-based and emulsion cosmetic systems. Establish the final use level and processing method in the complete formula.

Serums and Essences

In water-rich serums and essences, check hydration time, clarity, pH, preservative compatibility and finished-formula stability during development.

Toners and Lightweight Fluids

For toners and other low-viscosity formats, verify solution uniformity, colour, microbial stability and compatibility with the selected package.

Gels and Sheet-Mask Essences

In gel bases and sheet-mask liquids, gelling agents, electrolytes, humectants and preservatives may affect viscosity and uniformity. Complete a laboratory trial before production scale-up.

Creams and Lotions

In emulsions, introduce the material through a validated aqueous-phase process. Check compatibility with the emulsifier, active ingredients and preservative system. Monitor pH, viscosity and phase stability in the finished product.

NewHa® Hydrolyzed Hyaluronic Acid can soften the stratum corneum and accelerate skin metabolism. Inhibit oil secretion and other functions. The molecular weight of hydrolyzed hyaluronic acid is relatively low, HA powder can play the effect of transdermal absorption, deeply nourish the skin, improve skin elasticity and reduce wrinkles. Hyaluronic acid cosmetic grade powder can be widely used in cosmetics and care products, such as serum, lotion, mask, eye cream, sunscreen, spray and so on.

Facial Serums & Essences: Deep hydration and anti-aging effects.
Moisturizing Creams & Lotions: Improves water retention and smooth texture.
Facial Masks: Enhances skin suppleness and long-term moisturization.
Cleansers & Toners: Provides mild hydration and maintains balance after cleansing.
Makeup Products: Keeps skin hydrated and prevents flaking.

Hydrolyzed Hyaluronic Acid

Formulation and Handling Guidance

Introduce the powder gradually into a well-mixed aqueous phase. Avoid adding the full quantity to still water, as local over-concentration may slow wetting and create lumps. Allow sufficient hydration time before assessing clarity or viscosity.

Set the final addition order, mixing time, shear and processing temperature through a laboratory trial. Suitable conditions vary with the formula type, pH, electrolytes, emulsifiers and other polymers.

Check pH after the material is fully hydrated. The raw-material range should not be treated as a finished-formula pH instruction. Verify preservative compatibility and finished-formula stability in the intended package.

Discuss Your Formulation

Quality and Batch Documentation

The product TDS supports technical qualification and specification review. A lot-specific COA provides the actual test results for the applicable batch. An example COA should not replace the document for a future shipment.

If your project requires an additional test item, limit or method, include the requirement in the enquiry. State the destination country when requesting language-specific or market-related documentation.

Features

The NewHa® Hydrolyzed Hyaluronic Acid obtained by the enzymatic hydrolysis process has better biological activity and better permeability than the medium molecule macromolecule.

Hyaluronic acid powder can penetrate the stratum corneum and enter below the stratum corneum, quickly supplement nutrients to the cells, rapidly absorb through the skin, repair damaged cells, improve cell activity, increase skin moisture content, fully lock in water, improve skin dryness and dehydration, and delay skin aging.

It has a cosmetic effect and can also promote wound healing.

Product Documents

Document	Availability
Product TDS	Available for technical review
Lot-specific COA	Request for the applicable batch
SDS	Current availability and language version confirmed upon request
Destination-market documents	Scope confirmed upon request based on the country and document requirement

Packaging, Storage and Ordering Information

Hyaluronic acid raw material can be classified into three types based on molecular weight differences: Hyaluronic Acid LMW, Hyaluronic Acid MMW, and Hyaluronic Acid HMW. Although the chemical nature of the three is the same, due to the different molecular weights, They each have their own focuses in terms of mode of action, penetration ability and application scenarios. We are a professional manufacturer of hyaluronic acid, if you need any assistance, you can contact us at any time.

Packing: 1KG/BAG,25KG/DRUM.
Keep the material in its sealed package and protect it from moisture and contamination.
Store the product in a cool, dry place or at 2–8°C. Follow the current product label and applicable shipping documents for commercial handling.
Alternative packaging is reviewed according to the order quantity, shipping method and labelling requirement. Available options are confirmed with the current quotation.
MOQ, sample terms and lead time are confirmed with the current quotation. For an accurate offer, provide the target specification, estimated quantity, application, destination country, packaging requirement and document list.

Frequently Asked Questions

Yes. The available quantity, sample charge and freight arrangement are confirmed for the current request. Include the intended application, target molecular-weight requirement and destination country.

Provide the product name, target specification, estimated quantity, application, destination country, packaging and required documents. MOQ and the estimated dispatch schedule are confirmed with the current quotation.

The product TDS is available for technical review, and a lot-specific COA can be requested for the applicable batch. State the destination country, required document and language so current SDS and market-document availability can be confirmed.

Submit the required value or range, preferred method and intended application. Technical and commercial feasibility is confirmed before the requirement is included in a sample or quotation.

Yes. 1KG/BAG,25KG/DRUM. State any alternative pack size, labelling, outer-carton or pallet requirement in the enquiry; available options are confirmed with the current quotation.

TDS-of-Hydrolyzed Hyaluronic Acid CAS 9004-61-9

COA-of-Hydrolyzed Hyaluronic Acid CAS 9004-61-9

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